Clinical Pharmacy General Pharmacology

FDA Approved Drugs in 2020!

Jan 2nd, 2021
fda drugs approved 2020

FDA Approved Drugs in 2020

There were 53 FDA approved drugs in 2020.

These range from the ever-menacing COVID-19 to more obscure and rare diseases – such as Hutchinson-Gilford progeria syndrome; a condition characterized by the rapid onset of the appearance of aging in childhood.

Below we have put together the complete list of FDA drug approvals in 2020. Take some time to learn more about each drug and the condition with which it is now licensed to treat. As new medicines, there is still a lot to learn – particularly when it comes to adverse effects and drug interactions. Aspects of individual mechanisms may also be as-yet uncertain. And that is normal; it is part of the long and arduous – but nevertheless rewarding – process of drug development.

Unlike many others who failed to receive approval, these 53 medicines have come through a complex regimen of tests and regulatory barriers – demonstrating their clinical efficacy, pharmacology, and utility; as well as value in the treatment of both common and rare diseases. Many of these drugs may also become the first of what will become an established drug class.

So, with these factors in mind, let’s now take a few minutes to review all fifty-three of the FDA approved drugs in 2020.

Medicines Approved in 2020

MedicineActive IngredientIndication(s)
GemtesavibegronOveractive bladder
OrgovyxrelugolixAdvanced prostate cancer
Margenzamargetuximab (anti-HER2 mAbHER2+ breast cancer
KlisyritirbanibulinActinic Keratosis (face or scalp)
OrladeyoberotralstatHereditary angioedema
Gallium 68 PSMA-11Gallium 68 PSMA-11Prostate cancer detection / localization
Danyelzanaxitamab-gqgkRefractory or relapsed neuroblastoma
ImcivreesetmelanotideObesity; and control of hunger in patients with pro-opiomelanocortin deficiency
OxlumolumasiranHyperoxaluria type 1
ZokinvylonafarnibHutchinson-Gilford progeria syndrome
Inmazebatoltivimab, maftivimab, and odesivimab-ebgnEbola virus
GavretopralsetinibNon-small lung cancer
Detectnetcopper Cu 64 dotatate injectionDetection of certain kinds of neuroendocrine tumor
Sogroyasomapacitan-becoReplacement of endogenous growth hormone
Enspryngsatralizumab-mwgeNeuromyelitis optica spectrum disorder
ViltepsoviltolarsenDuchenne muscular dystrophy
OlinvykoliceridineAcute pain in certain adults
EvrysdirisdiplamSpinal muscular atrophy
LampitnifurtimoxChagas disease in patients < 18 years
Blenrepbelantamab mafodotin-blmfMultiple myeloma
Monjuvitafasitamab-cxixRelapsed or refractory diffuse large B-cell lymphoma
XeglyzeabametapirHead lice
Inqovidecitabine and cedazuridineMyelodysplastic syndromes
ByfavoremimazolamFor sedation
DojolvitriheptanoinTreatment of long-chain fatty acid oxidation disorders
ZepzelcalurbinectedinMetastatic small cell lung cancer
Upliznainebilizumab-cdonNeuromyelitis optica spectrum disorder
Tauvidflortaucipir F18Alzheimer’s disease diagnostic agent
ArtesunateartesunateSevere forms of malaria
Ceriannafluoroestrdiol F18Diagnostic imaging agent for breast cancer
QinlockripretinibAdvanced GISTs
RetevmoselpercatinibCertain kinds of lung and thyroid cancers
TabrectacapmatinibNon-small cell lung cancer
OngentysopicaponeParkinson’s disease during “off” periods
Trodelvysacituzumab govitecan-hziyMetastatic triple-negative breast cancer
TukysatucatinibAdvanced unresectable or metastatic HER2-positive breast cancer
KoselugoselumetinibNeurofibromatosis type 1
ZeposiaozanimodRelapsing forms of multiple sclerosis
IsturisaosilodrostatCushing’s disease
SarclisaisatuximabMultiple myeloma
Nurtec ODTrimegepantMigraine
BarhemsysamisulpridePrevention of post-operative nausea and vomiting
Vyeptieptinezumab-jjmrMigraine prophylaxis
Nexletolbempedoic acidHeterozygous familial hypercholesterolemia
PizensylactitolChronic idiopathic constipation (CIC)
TazveriktazemetostatEpithelioid sarcoma
Tepezzateprotumumab-trbwThyroid eye disease
AyvakitavapritinibUnresectable or metastatic GIST