Each week we compile all the latest pharmacology facts released on our social media platforms. This is great pharmacology for students, as these facts are bite-sized, random, and often important facts that all students of medicine should commit to memory.
- Carbonic anhydrase inhibitors, such as acetazolamide and dorzolamide are used in glaucoma. Acetazolamide is also used in altitude sickness.
- Renin inhibitors (eg. aliskiren) are used to treat essential hypertension. It prevents conversion of angiotensinogen into angiotensin I.
- Tamsulosin (Flomax) is an alpha-1a receptor antagonist used to improve urine flow in patients with an enlarged prostate (prostatic hypertrophy).
- Nitazoxanide is a broad-spectrum antiparasitic used to treat Cryptosporidiosis, Giardiasis, and amebiasis infections.
- Tinidazole (anti-parasitic) is used to treat trichomoniasis, giardiasis, and amebiasis and bacterial vaginosis. Side effects include upset stomach, bitter taste, itchiness.
- Drug antidotes: Acetaminophen (acetylcysteine), Anticholinergics (physostigmine), Benzodiazepines (flumazenil), Opioids (naloxone).
- Drug antidotes II: Heparin (protamine sulfate), Insulin (glucagon), Warfarin (vitamin K), Iron (deferoxamine).
- Azole antifungal drugs; Imidazoles: Clotrimazole - Miconazole – Ketoconazole; Triazoles: Fluconazole - Itraconazole – Voriconazole.
- Azole antifungal drugs work by inhibiting lanosterol-14-alpha-demethylase, the enzyme needed to convert lanosterol into ergosterol.
- Abortifacients are substances that induce abortion - examples of which include: - Mifepristone - Misoprostol – Methotrexate.
- Nabumetone is an NSAID that preferentially blocks COX-2. It is used in the treatment of osteoarthritis and rheumatoid arthritis.
Mnemonics and mindmaps are also another great way to commit pharmacology to memory. But if you’d like to learn more about specific drug classes, check out these more detailed articles for more information.
Check out last week's pharmacology facts here!