Pharmacology Facts (4-9 December)

Each week we compile all the latest pharmacology facts released on our social media platforms. This is great pharmacology for students, as these facts are bite-sized, random, and often important facts that all students of medicine should commit to memory.

If you haven’t already, be sure to check out our Facebook and Twitter feeds for all the latest articles, infographics, and facts. These facts were released during the period 4-9 December.

  • Bevacizumab is an angiogenesis inhibitor (inhibits VEGF-A) – it is used to treat various kinds of cancer such as colon, kidney, lung, and ovary.
  • Cetuximab (Erbitux) is an EGFR inhibitor used for colorectal cancer and head and neck cancer. It is given IV and has a half-life of 114 hours.
  • Trastuzumab (Herceptin) a monoclonal antibody used to treat breast cancer; it works by interfering with the HER2/neu receptor.
  • Cyclizine is an antihistamine used to treat nausea, vomiting and dizziness associated with motion sickness, vertigo and post-operative surgery.
  • Anticholinergic side effects include blurred vision, constipation, decreased sweating, dizziness, dry mouth and difficulty urinating.
  • The bleeding risk with aspirin increases in those who are older, who drink alcohol, who take other NSAIDs and who take blood thinners.
  • Paracetamol overdose initially focuses on replacing glutathione (something acetylcysteine provides) and decreasing further absorption of the drug (administering activated charcoal, for example).
  • Artesunate is drug used for severe cases for malaria (it is considered by WHO an 'essential medicine', but is not yet FDA-approved).
  • Tizanidine is a short-acting muscle relaxant medicine; an α2 adrenergic agonist; it is used for spasms/cramps caused by various disorders and injuries (multiple sclerosis, ALS, backpain, and nervous system injuries).
  • Tizanidine has also been linked to elevated liver enzymes and/or liver damage itself; it shouldn't be taken with CYP1A2 inhibitors.
  • Examples of CYP1A2 inhibitors: fluvoxamine, amiodarone, verapamil, cimetidine and oral contras – tizanidine is also contraindicated with fluoroquinolones such as ciprofloxacin, too.

Mnemonics and mindmaps are also another great way to commit pharmacology to memory. But if you’d like to learn more about specific drug classes, check out these more detailed articles for more information.

Take two minutes to check out last week's facts here!

By | 2016-12-12T19:44:15+00:00 December 9th, 2016|Weekly Facts|0 Comments

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