Each week we compile all the latest pharmacology facts released on our social media platforms. This is great pharmacology for students, as these facts are bite-sized, random, and often important facts that all students of medicine should commit to memory.
- CNS stimulants are contraindicated in patients with cardiovascular impairment such as uncompensated heart failure & severe coronary disease.
- Tapentadol is a centrally acting opioid analgesic; a drug which works as a mu-opioid agonist and a norepinephrine reuptake inhibitor (NRI).
- Bupropion is a drug used to treat depression and to help patient's quit smoking. It notably increases the risk of epileptic seizures.
- Linezolid is an antibiotic used to treat serious Gram-positive infections including VRE & MRSA. Long-term use linked with thrombocytopenia.
- Sumatriptan is used to treat migraine headaches. High doses can cause sulfhemoglobinemia, where blood turns green-black due to sulfur load.
- Aclinidium bromide - approved in the US in 2012 - is a long-acting antimuscarinic used in maintenance treatment for COPD.
- Lomitapide is a lipid-lowering drug that treats familial hypercholesterolemia - it inhibits microsomal triglyceride transfer protein (MTTP).
- Verapamil is a class IV antiarrhythmic drug, a drug that blocks voltage-dependent calcium channels. Its most common side effect is constipation.
- Mipomersen is an antisense drug that targets the mRNA for apolipoprotein B. It's used to treat homozygous familial hypercholesterolemia.
- Iohexol is a contrast agent used during coronary angiography. It comes at various concentrations - from 140 to 350mg of iodine per mL.
Mnemonics and mindmaps are also another great way to commit pharmacology to memory. But if you’d like to learn more about specific drug classes, check out these more detailed articles for more information.
Check out next week's pharmacology facts here!