Each week we compile all the latest pharmacology facts released on our social media platforms. This is great pharmacology for students, as these facts are bite-sized, random, and often important facts that all students of medicine should commit to memory.
- Azathioprine and mycophenolate mofetil are antiproliferative drugs used in the treatment of transplant rejection. Azathioprine is also used to treat rheumatoid arthritis, Crohn’s disease, and ulcerative colitis.
- Mycophenolate mofetil is derived from the fungi Penicillium stoloniferum and Penicillium echinulatum.
- Ketorolac is an NSAID used in the treatment of pain. Given the potent side effect profile, the medicine is only recommended for use in patients for 5 days or less (oral use).
- Nitrogen mustards, nitrosoureas, and alkyl sulfonates are three classes of drug under the wider church of alkylating agents – agents which are used in cancer chemotherapy. Alkylating agents work by attaching an alkyl group – CnH2n+1 – to DNA.
- Non-selective beta blockers should be avoided in patients with asthma because they can trigger a severe asthmatic attack.
- The antibacterial drug, imipenem, is administered with another agent, cilastatin. This latter agent prevents imipenem from being degraded by the renal enzyme, dehydropeptidase 1.
- Fusidic acid is an antibacterial used in the treatment of skin infections. It is only active against Gram positive infections (most skin infections are Gram positive in origin).
- Ziprasidone – an atypical antipsychotic – should be taken with food. Taking the drug without food reduces its bioavailability by up to 50 percent.
- Mefenamic acid should also be taken with food. It is an NSAID which, when taken without food, increases the risk of nausea, vomiting, and stomach upset.
Mnemonics and mindmaps are also another great way to commit pharmacology to memory. But if you’d like to learn more about specific drug classes, check out these more detailed articles for more information.
Take two minutes to check out last week's facts here!